Research on Polylactide (PLA): Toward Sustainable Materials and Biomedical Applications
Assoc. Prof. Yottha Srithep, PhD
Department of Manufacturing Engineering, Faculty of Engineering, Mahasarakham University
Research Background
Polylactide (PLA) is one of the most widely studied biodegradable polymers, derived from renewable resources such as corn and sugarcane. Its biodegradability, biocompatibility, and potential to replace petroleum-based plastics make PLA an attractive candidate for both environmental sustainability and biomedical innovations.
At Mahasarakham University, research on PLA focuses on improving its thermal stability, crystallization behavior, mechanical performance, and degradability, addressing the limitations that currently hinder its widespread applications.
Key Research Directions
- Stereocomplex PLA (SC-PLA):
- Blending poly(L-lactide) (PLLA) and poly(D-lactide) (PDLA) to form SC-PLA with higher melting temperature and improved mechanical properties.
- Potential uses in high-temperature packaging and biomedical scaffolds.
- PLA Blends and Nanocomposites:
- Introducing natural additives (e.g., epoxidized soybean oil, nanocellulose) to improve flexibility, toughness, and crystallization rate.
- Developing eco-friendly composites suitable for packaging and engineering applications.
- Biomedical Applications:
- Scaffold design for bone tissue and regenerative medicine.
- Surface modification and degradation studies for improved biocompatibility.
- Sustainability and Green Processing:
- Moving toward solvent-free processing methods.
- Exploring recycling and circular economy pathways for PLA-based materials.
Broader Impacts
- Environmental: Offering alternatives to petroleum plastics and reducing plastic waste.
- Economic: Creating opportunities for bioplastic industries in Thailand and ASEAN.
- Medical: Contributing to the development of advanced biomaterials for healthcare applications.
Future Outlook
The research team aims to expand collaborations with international partners, focusing on eco-friendly and multifunctional PLA materials. With growing global demand for sustainable solutions, PLA research is expected to play a vital role in shaping the future of both packaging and biomedical engineering.
Contact Information
Assoc. Prof. Dr. Yottha Srithep
Faculty of Engineering, Mahasarakham University
Email: [email protected]
Tel: +66910614566
